New Spectrophotometric Methods for the Simultaneous Determination of Irbesartan and Hydrochlorothiazide in Combined Dosage Forms

Abstract

Author(s): Josyula Sai Phani Kumar and Mukthinuthalapati Mathrusri Annapurna

The combination of Irbesartan and Hydrochlorothiazideis mainly used for the treatment of hypertension. New spectrophotometric methods have been developed and validated for the simultaneous determination of Irbesartan and Hydrochlorothiazide in pharmaceutical formulations (Tablets) by two methods i.e. simultaneous equation method and absorbance ratio method (Q?analysis) in phosphate buffer (p^H 7.5). Irbesartan and Hydrochlorothiazide have shown linearity over the concentration range 5-35 μg/ml and 0.2-40 μg/ml in both the methods.

20+ Million Readerbase

• Latest

Google Scholar citation report

Citations : 3403

Pharmaceutical Methods received 3403 citations as per google scholar report

Pharmaceutical Methods peer review process verified at publons