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High-performance thin layer chromatography: A powerful analytical technique in pharmaceutical drug discovery

Submitted by webadmin on Mon, 10/17/2016 - 16:43
Pharmaceutical Methods,2011,2,2,71-75.
Published:April 2011
Type:Symposium

High-performance thin layer chromatography: A powerful analytical technique in pharmaceutical drug discovery

Mahesh Attimarad, Mueen Ahmed K. K., Bandar E. Aldhubaib, Sree Harsha

Department of Pharmaceutical Sciences, College of Clinical Pharmacy, King Faisal University, Al-Ahsa, Saudi Arabia

Abstract:

Analysis of pharmaceutical and natural compounds and newer drugs is commonly used in all the stages of drug discovery and development process. High-performance thin layer chromatography is one of the sophisticated instrumental techniques based on the full capabilities of thin layer chromatography. The advantages of automation, scanning, full optimization, selective detection principle, minimum sample preparation, hyphenation, and so on enable it to be a powerful analytical tool for chromatographic information of complex mixtures of pharmaceuticals, natural products, clinical samples, food stuffs, and so on.